One Truth Serum contains TAM-818, a unique patented molecule discovered by award winning Telomere Biologist, Dr. Bill Andrews.

In the quest for a cure for ageing the scientific team at Sierra Sciences screened almost 300,000 compounds looking for the most effective. Several stood out and were grouped together into 39 different families. ‘818’, part of the group known as ‘Family Five’ was the strongest of all the compounds discovered. Dr. Andrews and his team used a technique known as medicinal chemistry to enhance the effectiveness and potency of the ‘818’ molecule.

The ‘818’ molecule was then handed over to experienced cosmetic scientists at Chase Life Extension Foundation who first modified it into a ‘cosmetic ready’ state and then encapsulated the ‘818’ molecule into a complex liposome, enabling delivery of the ‘818’ into the deepest layers of the skin. This sophisticated active ingredient is now what we call, TAM-818.

Clinical trials support the use of One Truth Serum with TAM-818, which may help to slow signs of ageing while significantly reducing the appearance of wrinkles and lines.

What does TAM-818 stand for?

TAM stands for Telomerase Activating Molecule and the ‘818’ is a nick-name because this was the 314,818th molecule that Sierra Sciences screened.

The back story of TAM-818:

The 314,818th molecule was actually screened at Sierra Sciences some years ago, back in 2010. It was special in that Sierra Sciences had commissioned this molecule to be made for them at a cost of $500,000 for only 50 grams! The investor who paid for and initiated this project had it in mind that it would be great for use in a skin cream. His sister was highly regarded in the beauty industry with knowledge of cosmetic chemistry and he spoke to her about it, a casual chat on the driveway one day. She heard nothing else about the project for years as the scientists had decided that the compound was too expensive to use and dismissed it.

It was during a regular Friday meeting that the potency of ‘818’ was questioned and revealed that the efficacy of this molecule is so remarkably strong only a small quantity was used to achieve the ground-breaking results shown at Sierra Sciences.  Suddenly the skincare project was once again on the table! It’s strength made it commercially viable. Rachael D’Aguiar was called and with a resounding ‘yes- of course she was still interested’ went about formulating the ideal serum to include TAM-818.   Her only caviot was that she had to complete the formulation by the time she gave birth to her second daughter! We’re still not sure how she did it (her company, Chase Life Extension Foundation was already busy with their successful supplement, Rewind, as well as her commitments as a guest speaker in the beauty industry) but the final formulation was indeed sent to Abich Labs in Italy just before baby number 2 was welcomed! And so while Rachael nursed a newborn her product, One Truth 818 Serum, was making history undergoing the most extensive clinical trials ever performed on topical telomerase induction – the type of scenario she is certain many women entrepreneurs can relate too.

With nearly 20 years experience in the beauty industry from owning her own salon/spa, to coaching and mentoring other business owners in the beauty industry, keynote speaking and hair and makeup artistry she had collected a wide variety what consumers and business owners wanted in a product. When it comes to a serum there were certain consensus opinions that she took into consideration when formulating:

Not too watery – it just runs between your fingers and is wasted.

I want to use it on my eye area – if its so good why can’t I use it where I have so many fine lines?!

Don’t dry to a filmy feeling – I need to be able to put makeup on – a serum should leave my skin feeling silky, not ‘ball’ off as I use my makeup brushes on top of it.

I don’t want to wait 5 minutes for it to absorb before I can put my moisturiser on – I’m too busy thanks!

If I want to smell like an overbearing floral bouquet I’ll use too much Eau De Parfum – don’t go overkill with the fragrance of a serum, please!

So what was the final result? Says Rachael “Most women who use One Truth 818 Serum will use either makeup or moisturiser, or both over top of it, so I needed to create a serum that was instantly absorbed so it could be layered over easily. The texture of One Truth 818 Serum is like velvet. It has a gel base, it’s not watery so you won’t waste any, it glides on like silk and is instantly absorbed. You can apply it all over your face and neck and include your eyes as it is non-irritating and it is a beautiful base to apply makeup over”. Of the eco-certified fragrance she adds “ One Truth 818 is not strictly for women, we have a strong male fan-base too and I needed to take this into consideration when choosing a fragrance. I’ve gone for a subtle citrus based scent which is refreshing but by no means over-powering”

“One of the biggest considerations was that there would be many different skin types wanting to use One Truth” explains Rachael “so I had to focus on benefits for all skin types.   So I formulated a super hydrating serum to compliment the inexplicable power of the TAM-818 as hydration is beneficial for all skin types. One Truth 818 Serum has been proven to assist with trans-epidermal water loss and I believe this, coupled with the restructuring abilities of TAM-818 is why we are seeing such excellent results on sensitive, sensitized and rosacea skins”.

We asked her to tell us a little about the formulation, here’s what she told us “Although One Truth is non-greasy it’s actually quite an oil-rich formula full of lecithin, sunflower, macadamia esters, jojoba and omega oils. In fact, One Truth contains over 95% naturally derived ingredients. Many of the women under 40 in the NZ trials felt they didn’t need to use their moisturiser on top of One Truth and were happy with the moisture and hydration provided by the serum alone. (FYI these trials were held mid-late summer). 2 pumps is enough for your face and neck and I recommend for best results to use twice a day. Your 50ml bottle should last approx. 10 weeks”.

She says yes, it’s her favourite product ever, she never leaves home without it and her skin has never looked better. “TAM-818 is a very special ingredient with a unique action. After 20 years in the industry and using every product under the sun I had never experienced anything like One Truth. I could literally see my wrinkles lifting back up to the surface again as if by magic. No fake plumping or removing any skin just literally reversing the damage that time had caused. Very real and scientifically proven it still felt like a miracle to witness! I am totally needle-phobic and never want to mess with my face or my natural expression. I think I represent many women’s feelings in that I like being animated and having ‘character’ to my face but I don’t like wrinkles! Now with true anti-aging topically using TAM-818 I’ll never have to resort to those kinds of interventions to continue looking young”.

Tried. Tested. The Truth.

Independent dermatological testing at Abich Laboratories in Italy showed that after 30 days* the appearance of forehead wrinkles decreased by 14.10%** while the appearance of crows feet decreased by 11.07%**

After 30 days skin firmness improved by 20.33%** and skin elasticity by 8.33%**

*Twice daily use
**Results given are the average, mean result of 100 volunteers aged 36 – 65 under scientific testing supervision.

Full One Truth 818 Serum Ingredients List:

Water, Jojoba Esters, Macadamia integrifolia Seed Oil, Ethyl Macadamiate, Isoamyl Laurate, Sodium Acrylates Copolymer, Glycerin, TAM 818, Helianthus Annuus (Sunflower) Seed Oil, Caprylhydroxamic acid, Glyceryl Caprylate , Hydrogenated Polyisobutene, Lecithin, Phospholipids, Polyglyceryl-6 Caprylate, Polyglyceryl-10 Stearate, Propanediol, Tocopherol, Isopropyl Myristate, Citric Acid, Potassium Sorbate, Sodium Phytate, Fragrance (EcoCertified), Limonene, Linalool.

Dermatologically tested. Non-sensitizing. Non-irritant. Non-toxic. Non-mutagenic.

Not tested on animals